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POM 1 br Previous studies have demonstrated that TRIM and IG
2021-03-03
Previous studies have demonstrated that TRIM25 and IGF2BP3 play an essential role in cancer cell proliferation [38]. For example, TRIM25 is a potent regulator of metastatic disease and associated with poor survival outcomes for breast cancer [22,39]. TRIM25 also acts as an on-cogene in colorectal
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br side effects and toxicity of free DOX
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side effects and toxicity of free DOX. However, no apparent weight loss was observed in other group conforming the safety of nanocomposites. H&E staining of the major organs (Fig. S14, heart, liver, spleen, lung, and kidney) further demonstrated nanocarriers with no tissue damage. In vivo safety o
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Ahsan N et al Comparative
2021-03-03
Ahsan, N., et al., 2018. Comparative effects of Bisphenol S and Bisphenol A on the development of female reproductive system in rats; a neonatal exposure study. Chemosphere 197, 336e343. Aiba, T., et al., 2018. Does the prenatal bisphenol A exposure alter DNA methylation levels in the mouse hippo
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In a Pap smear analysis
2020-08-30
In a Pap smear analysis, a feature can be defined as a piece of in-formation that is relevant for solving the computational task related to the Pap smear image analysis. Features extracted from the Pap smear images can be broadly classified as structural or textural features [28] and these include:
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br HPV oncogenes decrease sub erythemal UV
2020-08-30
3.2. HPV oncogenes decrease sub-erythemal UV-induced apoptosis This increased sensitivity is likely due to HPV E6 and E7 disrupting 205640-90-0 regulation and causing abnormal activation of DNA damage response genes. However, HPV oncogenes also mitigate the deleterious consequences of DNA dama
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br Western blot analysis br For Western blot analysis total
2020-08-30
2.3. Western blot analysis For Western blot analysis, total protein was extracted using radioimmunoprecipitation assay buffer (50 mM Tris-HCl, 150 mM NaCl, 20 mM EDTA, 1% NP40, 0.1% SDS, 1 mM Na3VO4, 1 mM NaF, and 1 mM phenylmethylsulfo-nylfluoride) (Invitrogen Carlsbad, CA) supplemented with t
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Staurosporine br Intracellular localization br At a
2020-08-30
3.2.3. Intracellular localization At a very early time point (1 h), despite the different internalization kinetics recorded through flow cytometry, chitosan/HA and Nanocin/ HA NP did not showed a markedly different behavior: both of them were internalized in similar amounts with some, possibly
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br Our mean whole heart doses are consistent with those
2020-08-28
Our mean whole MDMB-CHMICA M2 doses are consistent with those of other published estimates for similar regimens (Table E7; available online at https://doi.org/10.1016/j. prro.2019.01.004). Dosimetric uncertainties are larger for cardiac segment doses than for mean whole heart doses because segmen
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Phan NN Wang CY Chen CF
2020-08-28
[48] Phan NN, Wang CY, Chen CF, Sun Z, Lai MD, Lin YC. Voltage-gated calcium channels: novel targets for cancer therapy. Oncol Lett 2017;14(2):2059–74. [49] Buckner CA, Buckner AL, Koren SA, Persinger MA, Lafrenie RM. Inhibition of cancer cell growth by exposure to a specific time-varying electroma
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In Korea most of cases are squamous
2020-08-28
In Korea, most of cases ActinomycinD squamous cell carcinomas (SCC) (ap-proximately 80%) followed by adenocarcinomas (ADC), although an increase in the proportion of ADC was reported (from 8.9% in 1993 to 16.1% in 2009). Unlike a downtrend in ASR-incidence of SCC (from 14.1 per 100,000 in 1993–7.
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br In summary problems with body image seemed to
2020-08-18
In summary, problems with body image seemed to persist long time post-RRM, regardless of previous breast cancer or not. A decline in ‘General health’ appeared over time, but no HRQoL dif-ferences were found at the long-term follow-up between women with and without cancer. The long-term results of
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br Materials and methods br Human tissue
2020-08-18
2. Materials and methods 2.1. Human tissue specimens and cells Formaldehyde-fixed paraffin-embedded (FFPE) BC tissues and un-paired mammary hyperplasia (non-tumor tissues) were randomly col-lected from patients who had undergone surgery at the Shaanxi Provincial People's Hospital in China. C
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br Refer iframe width height src https www
2020-08-18
References ACCEPTED MANUSCRIPT 2. Wolchok JD, Chiarion-Sileni V, Gonzalez R, et al. Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma. The New England journal of medicine. Oct 5 2017;377(14):1345-1356. 3. Hellmann MD, Rizvi NA, Goldman JW, et al. Nivolumab plus
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br Preparation of PMDIs PMIs PMDs and DINPs br
2020-08-18
2.2. Preparation of PMDIs, PMIs, PMDs, and DINPs The synthesis process is shown in Fig. 1. PLGA nanoparticles con-currently entrapping DOX and ICG (DINPs) were created by the oil-in-water emulsion solvent evaporation method. In brief, 60 mg PLGA, 1 mg DOX, and 1 mg ICG were solubilized in 4 mL
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br Moreover As shown in
2020-08-18
Moreover, As shown in the Fig. 6, the cytosolic cytochrome c in 56-75-7 treated with BHAE increased remarkably campared to the control cells (**P ≤ .01). BHAE induced elevation of lipid peroxidation rate, a marker of reac-tive oxygen species (ROS) and an increase of cytosolic cytochrome c level