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  • br Conclusions br This is the first study to investigate

    2020-08-14


    Conclusions
    This is the first study to investigate the relationship between nicotine dependence and genotypes according to smoking status in Chinese patients with lung cancer. Health care workers should pay attention to the duration of smoking and the initial age of smoking of patients who failed to quit smoking after diagnosis of lung cancer. SNPs of CHRNA3 (rs578776) and CHRNA4 (rs1044396 and rs2229959) were associated with the success of smoking cessation after the diagnosis of lung cancer. Clinical practice points
    The duration of smoking in the failure to quit smoking group was significantly higher than those in the successful smoking cessation group.
    The initial smoking age in the failure to quit smoking group was significantly younger than those in the successful smoking cessation group.
    Disclosure The authors declared no potential conflict of interest.
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    ACCEPTED MANUSCRIPT
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