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br journal homepage www elsevier com locate ejps br
2020-08-04
journal homepage: www.elsevier.com/locate/ejps Aryl-urea fatty acids that activate the p38 MAP kinase and down-regulate T multiple cyclins decrease the viability of MDA-MB-231 breast cancer cells☆ Yassir Al-Zubaidia,1, Curtis Pazderkab,1, Nooshin Koolajia, Md Khalilur Rahmana, Hassan Chouca
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br MODEL br ARHGEF as a novel biomarker br IHC
2020-08-04
+ MODEL ARHGEF38 as a novel biomarker 5 IHC studies to determine the expression of ARHGEF38 and Ki67 in PCa IHC was performed to detect the expression of ARHGEF38 and Ki67 (encodes a nuclear protein that is associated with and may be necessary for cellular proliferation), in differ-ential
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br quite robust br Figure Comparison of
2020-08-03
quite robust. Figure 6. Comparison of two ROC curves generated using (a) training dataset and (b) testing dataset. After applying an operating threshold (T = 0.5) to divide the test cases into two predicted Nifurtimox being malignant or benign, we generated two confusion matrices of test
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br Morphological analysis of nano liposomes br TEM
2020-08-02
3.2. Morphological analysis of nano-liposomes TEM images detailed the formation of regular, consistent NLS as illustrated in Fig. 1(I). Fluorescence microscopy was employed to con-firm the restoration of NLS structure and subsequent conversion to NLBs. The fluorescence micrographs of the CHO-NL
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Herboxidiene br a step to explore the effect
2020-07-30
a step to explore the effect of Mar-C on transcriptional factors, including NF-κB, TFEB, TFE3, STAT1, STAT3, GATA4 and C/EBPβ, which are able to modulate SASP [28–31]. The mRNA level of STAT1, STAT3, GATA4 and C/EBPβ were not significantly altered upon Mar-C treatment (Fig. 5E). Nuclear translocat
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br METHOD DETAILS br Cloning br
2020-07-28
METHOD DETAILS Cloning The human kinase library plasmid kit, containing open reading frames (ORFs) in Gateway Entry vectors, was provided by William Hahn and David Root (Johannessen et al., 2010; Yang et al., 2011) via Addgene (Kit # 1000000014). The human phosphatase library was obtained fr
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br Results br A total of patients with stage
2020-07-28
Results A total of 211 patients with stage III NSCLC who were treated with definitive CRT met our inclusion criteria. Table 1 summarizes the baseline patient demographics and treatment characteristics. The median age at diagnosis was 63 years (range, 36-84 years), and 51% were female. The major
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Gene br Stage specific mRNA and
2020-07-27
Gene 712 (2019) 143961 2.2. Stage specific mRNA and lncRNA selection from TCGA followed by mRNA – lncRNA-miRNA interaction network generation TANRIC provided the Solasodine data of lncRNAs from TCGA (Li et al., 2015) and that of mRNAs was directly derived from TCGA whereas the clinical dat
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br Evaluation of intracellular reactive oxygen species
2020-07-27
2.9. Evaluation of intracellular reactive oxygen species (ROS) generation MDA-MB-231 cells (1 × 105 cells/mL), under standard cultural conditions, were seeded in a 6-well plate containing RPMI media and allowed to attach for 24 h. After this, the cells were treated for 72 h with different conce
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br Corresponding author br E mail address
2020-07-04
Corresponding author. E-mail address: [email protected] (S. Pizzimenti). 1 Martina Daga and Stefania Pizzimenti contributed equally to this work. 2 Co-last authors. Introduction Ailanthone (Aila) [(1β,11β,12α)-11,20-Epoxy-1,11,12-trihydrox-ypicrasa-3,13(21)-diene-2,16‑dione
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br research Washington DC American Psychological Association
2020-07-04
research. Washington DC: American Psychological Association; 2004. 68. Black E, White C. Fear of recurrence, sense of coherence and posttraumatic stress disorder in haematological cancer survivors. Psycho-Oncology. 2005;14:510–515. 69. Kim S, Son BH, Hwang SY, et al. Fatigue and depression in
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br the KCTD CDK interaction and inactivates
2020-03-24
the KCTD12-CDK1 interaction and inactivates CDK1 in cancer cells. 3.4. Adefovir dipivoxil induces G2 phase Sorafenib arrest Given that the interaction of KCTD12 and CDK1 is necessary for G2- M transition during mitosis [20,43], we postulated that AD might have an important effect on ca
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br Defining the genetic determinants of ABCC upregulation co
2020-03-24
Defining the genetic determinants of ABCC3 upregulation could identify a cohort of patients that might benefit from ABCC3 targeted therapy. We therefore investigated a possible mechanistic link between ABCC3 regulation and mutation of key genes in PDAC. Mutations in TP53 are present in 50–70% of P
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br Discussion br Detection and prioritization of cancer rela
2019-11-12
4. Discussion Detection and prioritization of cancer-related coding genes, miRNAs and their interactions play crucial role in the understanding of the ge-netic architecture of cancer and improve the accuracy of diagnosis. Different from other methods, we applied an unsupervised learning based b
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GSK126 br Clinical Breast Cancer Vol No e Crown
2019-11-11
Clinical Breast Cancer, Vol. 19, No. 2, e319-26 Crown Copyright ª 2018 Published by Elsevier Inc. All rights reserved. Keywords: Cancer care, Cancer well-being, Complementary medicine, Physiotherapy, Reflexology Background It is widely accepted that practices akin to reflexology have been em